nanocarrier相关论文
The emergence of drug-resistant cancer cells together with the toxicity side effect of chemotherapy agents are the major......
Co-Delivery of a π-π Stacked Dual Anticancer Drug Combination with Nanocarriers for Overcoming Multi
Despite progress, combination therapy of various functional drugs to enhance the efficiency against multidrug resistance......
Ferritin is a major iron storage protein found in humans and most living organisms.Each ferritin is comprised of 24 subu......
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Purpose Transplantation of mesenchymal stem cells for ischemic stroke therapy has had modest success in the preclinical ......
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Effect of chitosan based glycolipid-like nanocarrier in prevention of developing acquired drug resis
Multiple treatment strategies were frequently applied in anti-tumor therapy in clinic.However,numerous tumors developed ......
Evaluation of Anti-Inflammation Effect of Tea Polyphenol-Contained Nanoparticles for Dry Eye Syndrom
Dry eye syndrome(DES)is a common disease causing by instable tear film induce ocular surface inflammation.In ophthalmolo......
Stimuli-responsive surface charge reversion enhanced endocytosis and delivery efficiency for tumor d
Effective delivery of probes and drugs to tumor cells remains major challenge for cancer diagnosis and treatment.Nanopar......
Biomimetic Nanocarrier for the Intracellular Delivery of Imaging and Therapeutic Agents in Solid Tum
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The last few decades have witnessed the eme rgence of a very large variety of engineered nanomaterials.However,it is far......
The blood brain barrier represents a formidable obstacle for the transport of most systemati-cally administered neurodia......
卵巢癌是女性生殖系统最常见的恶性肿瘤之一,早期起病隐匿,确诊多为中期晚,致死率高。纳米材料因其直径小、分布均匀,经表面修饰后的纳......
RNA interference(RNAi)targeting lethal genes in insects has great potential for sustainable crop protection.Compared wit......
Mitochondrion targeting peptide-modified magnetic graphene oxide delivering mitoxantrone for impairm
In this study,we prepared mitochondrion targeting peptide-grafted magnetic graphene oxide(GO)nanocarriers for efficient ......
Deoxyribozyme(or denoted as DNAzyme),which is produced by in vitro screening technology,has gained extensive research in......
,Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current pe
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Ocular diseases include various anterior and posterior segment diseases.Due to the unique anatomy and physiology of the ......
本文通过对荣华二采区10...
Design of nanocarriers for efficient cellular uptake and endosomal release of small molecule and nuc
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Stimuli-responsive nitric oxide generator for light-triggered synergistic cancer photothermal/gas th
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Multiarm Star Poly(ε-caprolactone) with Hyperbranched Polyamidoamine as Core Capable of Selective Ac
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
铁蛋白是广泛存在于几乎所有生命体中的储铁蛋白,具有储存和转化铁、维持细胞铁代谢平衡以及保护细胞免受氧化损伤等功能。铁蛋白......
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以大米蛋白为原料,经胰蛋白酶酶解后制备纳米载体,以大豆苷元为输送对象,构建了大米蛋白酶解物—大豆苷元的纳米输送体系,通过试验......
目的:制备一种具有光热/pH双响应的核—壳结构纳米载药体系。方法:以水热法合成硫化铜纳米粒(CuS),然后在碱性条件下通过自聚合反......
采用水热法在氧化石墨烯(GO)表面生长MoS2纳米片并枝接聚乙二醇(PEG)以改善其生物相容性。通过傅立叶变换红外光谱、透射电子显微......
目的血脑屏障(blood-brain barrier,BBB)是一道天然的生理屏障,可保护中枢神经系统免受外来异物的伤害,同时限制了药物的递送。本......
[目的]评价人血清白蛋白纳米颗粒载体以及林源活性成分纳米颗粒制剂的安全性。[方法]以人血清白蛋白制备纳米颗粒载体,包埋红豆杉......
肿瘤微环境与肿瘤的发生发展密切相关,壳聚糖以其生物降解性和生物相容性而成为良好的纳米载体,现阶段纳米递送系统靶向的方法有主......
目的制备Fe3O4@ZnAl2O4:Eu^3+@mSiO2-APTES纳米载体并测定其对药物梣酮的负载和释放过程的热量变化.方法通过直接沉淀法制备Fe3O4@......
采用薄膜水化法制备了包覆绿色油溶量子点和红色水溶量子点的硅质体,红色量子点包覆于硅质体内腔中,绿色量子点包覆于类磷脂双层中.......
神经胶质瘤是颅内最常见的恶性肿瘤,占所有颅内肿瘤的46%.由于神经胶质瘤呈侵润性生长,故仅通过传统手术难以做到全部切除,因此,采......
文章采用温和的方法合成可精细调控不同尺寸的介孔二氧化硅纳米微球。香精被负载在介孔二氧化硅微球中,在纳米微球表面包覆一层聚......
优异的带有原位监测功能的智能药物递送系统(DDS)的设计合成,对于癌症临床诊断治疗具有十分重要的意义。在该工作中,将具有表面增......
利用纳米技术改进农药递送系统,开发新型缓释纳米农药,高效保护农作物的同时可以减轻密集性使用低效的传统农药给环境和非靶标生物......
【目的】研究RGD修饰、MRI可视的纳米载体(RGD-PEG-g-PEI-SPION)靶向传输Survivin siRNA至肝细胞癌抑制裸鼠肝癌生长的作用;探讨RG......
Using Au6 cluster and cyclooctaglycine model for gold nanoparticle(AuNP) and cyclic peptide(CP), twelve configurations f......
pH响应性药物释放体系的构建对于疾病的靶向诊疗具有重要意义。特别是,以pH响应性纳米载体材料为封堵装置封装药物,构建pH响应性药......
“刺激响应型”纳米载体是一类功能性聚合物,具有随外界环境变化而结构或性质改变的特征,在药物/基因传递方面具有重要的应用价值,......
智能纳米靶向释药载体能对外界环境的温度、pH值、电、磁、化学物质等的刺激信号做出响应,并控制药物按设定目标释放。根据不同机......
Transdermal drug delivery is impeded by the natural barrier of epidermis known as stratum corneum.This limits the route ......